Cheek cells are squamous epithelial cells. The addition of stains to cheek cells enables the observer to more clearly see different structures in the cells. There are many different stains that can be used to observe cells. These include the following:
- One of the most common stains used for observing cheek cells is methylene blue. Methylene blue stains DNA in the cell. This causes the nucleus of the cell to appear blue, while the cytoplasm remains clear or turns a very pale blue.
Eosin stain can be used to study the cytoplasm. Eosin stains the cytoplasm, while leaving the nucleus unstained.
Sudan stain can be used to stain lipids that are present in cell and organelle membranes.
Toluidine blue stains the nucleus and defines cell organelles. Toluidine blue is often used to scan for cancer cells which tend to have extra DNA in their nuclei.
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